If Sam Raimi’s fourth Spider-Man film would have happened we would have got to see John Malkovich take on the villainous role of Vulture. Unfortunately the movie fell apart and Sony Pictures decided to reboot the whole franchise with a younger High school Spider-Man for a younger generation. Malkovich recently did an interview in which he talks about Spider-Man 4 and his missed opportunity.
Well, I think a lot of the people who sort of follow that genre… I'm not sure, I never really spoke with Sam about this, but I'm not sure they -- maybe the kind of fanbase, the fanboys -- either didn't approve of that character as an adversary for him to some extent. Or maybe the studio. Or maybe that was totally unrelated to why it fell apart.
If you didn’t know already, Malkovich was also up for the role of Green Goblin in the first Spider-Man film. The part ultimately went to Willem Dafoe, so this is technically the second time Malcovich has been burned by Spider-Man.
Yes, [I was disappointed]. But because I like Sam and I like Toby [Maguire] and all that stuff, and the producers, two of whom I'd met before because I'd been offered the first [film]… I came to like them, so sure why not? But it didn't play out.
He goes on to say that Raimi has offered him a couple different roles over the years but it’s never worked out for a variety of reasons. That’s a shame, maybe one of these days we’ll see Malkovich and Raimi work together on a film, but it wont ever be a Spider-Man film.