Oscar Isaac’s Frankenstein Brings His First Creation to Life in Haunting New Clip from Guillermo del Toro’s Adaptation
Netflix released a new clip Guillermo del Toro’s upcoming Frankenstein, and it’s as eerie and mesmerizing as you’d expect. The clip was introduced by Oscar Isaac during his recent appearance on The Tonight Show Starring Jimmy Fallon, giving audiences their first real taste of Victor Frankenstein’s early experiments with reanimation.
The scene shows Victor revealing his “Proto-Creature” to a skeptical group of colleagues. The experiment is a grotesque assembly of a head, torso, and one arm, and it manages to catch a ball tossed its way, before letting it drop lifelessly to the floor.
It’s a chilling moment that perfectly captures the film’s blend of tragic humanity and unsettling science, a hallmark of del Toro’s style.
In a recent conversation with Backstage.com, Isaac opened up about the emotional themes that drive the story and his collaboration with del Toro.
“Early on, we talked so much about our fathers, and the way that pain gets passed down,” Isaac explained. “[The conversation] was always emotionally connected to everything being a reaction and an investigation of the world that one is born into.”
He went on to add, “[Del Toro and I] talked a lot about wanting to defy our fathers, and nature, and the future, and death. The defiance of death is a big one. The ‘[frick] it’ attitude, the willingness to destroy because one can’t sit in the pain or the fear of being seen, of actually being seen. You’d rather self-immolate.”
That raw, emotional defiance seems to be at the core of Frankenstein, which tells the story of a brilliant but prideful scientist who brings a creature (Jacob Elordi) to life, setting off a tragic spiral that consumes both creator and creation.
For del Toro, this project is personal. He said: “This film concludes a quest that started at age 7, when I saw James Whale’s Frankenstein films for the first time. I felt the jolt of recognition in that seminal moment: Gothic horror became my church, and Boris Karloff my Messiah,” the filmmaker said when the adaptation was first announced.
With its gothic visual style, emotional depth, and powerhouse performances, Frankenstein looks like it’s going to deliver a haunting yet emotional story.
The film will receive a limited theatrical release on October 17, before streaming globally on Netflix starting November 7.
A new clip from Guillermo del Toro’s ‘FRANKENSTEIN’ starring Oscar Isaac, Mia Goth and Jacob Elordi has been released. 🎥
— Film Crave (@_filmcrave) October 21, 2025
Releasing November 7 on Netflix. pic.twitter.com/24hdf8s4VC